Protein Labeling & Cross linking starting from 500 €

Explora’s custom protein labeling & crosslinking service provides personalized solutions designed to supply researchers with the widest choice of labels and cross linkers to meet their specific needs. Protein modification and crosslinking has emerged as a powerful tool for several different application field such as:

  • Enzyme & Antibody modifications and conjugations (biotin, chromo- and fluorophores, PEGgylation)
  • Oligo modification and labeling
  • Nanoparticle functionalization (e.g gold-labeled, magnetic nanoparticles, silica particle)
  • Surface immobilization (e.g. Microtitre wells, silica and gold slides)
  • Development of ‘small’ molecule drug & enzyme conjugates to therapeutic antibodies
  • Modification of key properties of therapeutic proteins to optimise PK/PD behaviour
  • In-vivo protein trafficking and subcellular localization
  • Conjugated biopharmaceuticals for targeted delivery of cytotoxic agents

Custom labeling fees start at €500 and include the conjugation of up to 1 mg of antibody or protein. On your behalf we carry out:

  • Biomolecule-low molecular weight compounds labeling (e.g. protein-biotin, digoxigenin, FITC) see here a complete list of in house LMW compounds
  • Biomolecule-biomolecule conjugation (e.g. antibody-HRP or protein-oligo)
  • Immobilization on solid supports (e.g. protein-magnetic nanoparticles, antibody-beads)

With a broad range of reagents:

  • Fluorescent labels
  • Chromophores
  • Photoactivated labels
  • Photolabile labels
  • Cleavable labels

Furthermore, Explora can support you in analyzing critical variables affecting conjugate behaviour:

  • Type of conjugation reaction: site-specific vs. random coupling
  • Site of conjugation: to reduce steric hindrance, minimize negative impact on folding and activity
  • Conjugate stoichiometry
  • In vivo conjugate behaviour: cleavable vs. non-cleavable labeling
  • Immunogenicity and In vitro stability of the linker group


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If you are looking for a reliabile custom protein expression service you may want to have a look to our all-included protein expression service.